منابع مشابه
Targeted Therapy of Breast Cancer.
improve the efficacy of antihormonal therapy and may overcome endocrine treatment resistance at least temporarily in many patients. However, the impressive array of possible treatment combinations and sequences warrants an enormous amount of further research to identify optimal treatment algorithms. Further research will also have to focus on the exploration and establishment of predictive fact...
متن کاملTargeted cancer therapy: review article
Cancer is one of the most dangerous health problems of today modern societies which has an increasing rate especially in developing countries. There are many diverse ongoing treatment attempts trying to defeat cancer. Despite that, scientists have been unable to find a permanent cure for this disease. In many cases although there is a successful first response in patients, cancer cells are fina...
متن کاملTargeted Therapy in Breast Cancer.
Currently targeted drug selection in breast cancer is exclusively based on estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor (HER2) expression mainly of the primary tumor, even if metastatic disease is actually treated. Retrospective data indicate discordance regarding those factors between primary tumors and corresponding metastatic lesions in up to...
متن کاملTargeted Therapy of HER2-Negative Breast Cancer.
Personalized and targeted treatments are the most discussed topics in oncology. However, how much personalized medicine is standard of care nowadays and how much is part of our hope for a better future? So far, only a few targeted therapies are available in daily practice for the treatment of human epidermal growth factor receptor 2 (HER2)-negative breast cancer. And even for these few targeted...
متن کاملTargeted therapy for HER2 positive breast cancer
INTRODUCTION Breast cancer is the second most common cause of death for women behind lung cancer and the most common cause of cancer deaths for women aged 45-55 years old (CDC.gov 2012). Although there continue to be enormously large numbers of disease incidence, deaths have been declining due to the disease with two hallmark time frames. The first occurred during the mid to late 1980's when ho...
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ژورنال
عنوان ژورنال: Oncology Research and Treatment
سال: 2016
ISSN: 2296-5270,2296-5262
DOI: 10.1159/000444685